Growing More Hair By Michael Mooney - Updated June, 2013.
Iron And
Hair Loss
Several studies have shown associations with low body stores of iron and hair loss. These include studies with women. When I interviewed one of the world's authorities on hair loss, Gary Perrault, MD, of Beverly Hills, California, he told me that one of the first things he looks at when there is hair loss is the person's body stores of iron, as measured by the blood test called "ferritin." If ferritin is below 40 ng/mL he recommends that the person supplement with iron to get their ferritin level up. However, he says, hair does even better at 70 ng/mL. This can require high dosage iron supplementation, perhaps 100 mg a day, as determined by your doctor. However, supplementation with as little as 24 to 48 mg per day has also been used. How much do you need? It is best to work with your doctor doing blood tests to determine this. Ask them to test "ferritin."
I Took Extra Iron (Updated November, 2006)
I have been taking a very high-potency anti-aging multi-vitamin that contains 40 mg of iron carbonyl since 1976. Since I had been battling a little bit of hair loss and my ferritin measured 22 ng/mL in May, 2006 when I spoke with Dr. Perrault, I began to add extra iron to my current regimen. Apparently I was a poor iron absorber.
I added iron as an extra 100 milligrams of iron carbonyl, twice a day, three days per week, so it amounted to an extra 200 mg on three days per week.
I didn't take it every day because it's a large dose and I didn't want to load my body with a large dose every day.
Ask your doctor before taking high dose iron for any reason.
As of October, 2010, I found that I only needed to take an extra 50 mg of iron carbonyl every other day, made by Rexall Sundown. This is only one of a few sources of iron carbonyl that I am aware of. It is available on the internet and from a few drugs stores around the USA.
Iron Formsand Constipation
I found that iron protein succinylate caused acute constipation at this high dose. When I switched to iron carbonyl, there was almost no problem with constipation. Iron carbonyl also has far less potential for toxicity than other forms of iron, although iron toxicity rarely occurs and is somewhat exaggerated.
Again, it is best to work with your doctor and get a ferritin blood test to determine how much iron you might need and take another test a couple months after you are taking a specific dose consistently to check and see if that dose is working for you.
Low Ferritin
If you measure as having low low ferritin even though you are consuming what might seem to be enough dietary iron, iron absorption is between about 2% and 20% for non-meat food sources of iron and between about 3% and 10% percent for supplemental forms of iron. Absorption of these forms of iron can be reduced significantly by various dietary components [1,3,11-15].
Iron from meat, called "heme iron," absorbs between about 15% and 35% and is not affected by dietary components. [15]
Update: In 2013 I found that I do not need to supplement with extra iron as my blood tests show that my ferritin is consistently at 70 ng/mL or above. It has stayed at this level without iron supplementation for several months now. I will continue to monitor it with blood tests and either supplement or not, as needed.
Researchers at Cleveland Clinic have noted iron's role in healthy hair, too. Read their press release below.
Low Iron Could Help Spur Baldness
WEDNESDAY, May 31 (HealthDay News) -- Could iron deficiency be key to baldness?
The answer is yes, according to researchers at the Cleveland Clinic, who reviewed scientific literature on the connection published over the past 40 years.
"If doctors can understand fully the relationship between iron deficiency and hair loss, then they can help people regrow hair more effectively," study leader Dr. Wilma Bergfeld, head of clinical research in the department of dermatology, said in a prepared statement. "We believe that iron deficiency may be related to many forms of hair loss and that people may need higher levels of iron stores than previously thought to regrow hair."
The review of data suggests that iron deficiency may be linked to several of the most common kinds of hair loss. However, there is not enough evidence to suggest universal screening for iron deficiency in hair-loss patients and further research is required, the researchers said.
The findings appear in the May, 2006 issue of the Journal of the American Academy of Dermatology. (Trost, et al. Volume 54, Issue 5 , Pages 824-844, May 2006)
Iron deficiency is the most common nutritional deficiency in the United States. It can be caused by inadequate dietary intake of iron, excessive menstrual bleeding, and other forms of blood loss. Treatment includes adequate dietary intake of iron and, when appropriate, iron supplements.
Doctors at the Cleveland Clinic routinely screen for iron deficiency in patients with hair loss. If iron deficiency is detected and treated in the early stages, patients may be able to grow hair more effectively, the researchers said.
-- Robert Preidt
SOURCE: Cleveland Clinic news release, May 15, 2006
For your viewing, I quote from Clinical Pearls One Liners, March 2003. Clinical Pearls is one of the periodicals I subscribe to for its evaluation of medical journal studies that focus on dietary supplements and complementary and alternative medicine.
From a review of a study by DH Rushton, MD.
Published in Clinical and Experimental Dermatology, 2002; volume 27, pages 396-404.
Iron, Lysine, Biotin
Iron supplementation at 24
to 48 mg per day, which raises
serum ferritin up to at least
70 mcg/l with the erythrocyte
sedimentation rate being >10
mm/hour, plus 1½ to 2 grams
of lysine daily have been shown
to have a positive benefit in
slowing hair loss. Using 1 to
2 mg per day of biotin may also
be of benefit, along with essential
fatty acids.
For More Hair Count
At this time, this might be the most potent effector of better hair count, meaning more healthy hairs.
An eight-month human study showed that subjects taking Tocomin SupraBio ® Tocotrienols experienced better than 34 percent average improved hair count.
I and close friends noticed a definite increase in my own hair thickness after about five months. While I started out taking 3 capsules every morning, I am taking 4 or 5 capsules a day now.
The directions says to take one or two capsules per day, but I generally take more than "as directed" when the ingredient appears to be very safe and potentially very beneficial for an anti-aging antioxidant effect.
Why Tocotrienols Might Work
How tocotrienols might work to increase hair count involves oxidative stress, caused by reactive oxygen species (ROS), such as super oxide, a tightly controlled inflammatory agent that the immune system deploys to kill invading microorganisms. A study by Naziroglu and Kokcam showed that there was an association between oxidative stress and hair loss.
As we age or because of nutritional deficiences of zinc, copper or manganese, we tend to make less superoxide dismutases (SOD), which control superoxide's potential to damage tissue, including damaging hair follicles.
As well, aging and nutritional deficiencies reduce production of glutathione peroxidase, an antioxidant enzyme, which also might protect hair follicles from oxidative damage.
Therefore, shampooing with Nizoral should be considered. Only use it two or three times a week or you might get little red bumps on your scalp.
Summary and Recommendations
To summarize my suggestions for thicker, healthier hair, increased hair count and a potential darkening of grey hair, in order of what I think is most effective:
1. Get a ferritin blood test and take supplement iron if you need to get ferritin above 40 ng/mL with 70 ng/mL being more optimal. Whatever iron dose you and your doctor select, ask your doctor to re-test you every few months to find out if that dose brings your ferritin level up enough;
2. Take Jarrow Toco-Sorb or Toco-8 orSuper Absorbable Tocotrienolsor Healthy Origins Tocomin SupraBio - they are all made from the same raw tocotrienol materials under license from Carotech;
3. Use Nizoral shampoo two or three times a week;
4. Take 2,000 mcg of biotin a day;
5. Take 2,000 mg of lysine a day;
6. Consider taking a strong multivitamin/multimineral supplement, as all reactions in the body are nutrient dependent, so nutrient deficiencies can compromise any bodily function.
Disclaimer: The information contained in this publication is for educational purposes only, and is in no way a substitute for the advice of a qualified medical doctor, registered dietitian, certified nutritionist, or exercise physiologist. When you ask any health care professional to help you make decisions about your personal healthcare, I recommend that you show them the information you find here because they may not be aware of it and the scientific studies that support it. Appropriate medical therapy and the use of pharmaceutical or nutritional compounds should be tailored for the individual as no two individuals are alike. I do not recommend self-medicating with any compound as you should consult with a qualified medical doctor, preferably one who is knowledgeable about nutrition and complementary/functional medicine who can determine your individual situation. Any use of the information presented in this publication for personal medical therapy is done strictly at your own risk and no responsibility is implied or intended on the part of the contributing writers, or the publisher.