Brush MG, et al. Pyridoxine in the treatment of
premenstrual syndrome: a retrospective survey in 630 patients. Brit J Clin Pract 1988;l42(11):448-4562.)
Consult your doctor about the use of higher dose Vitamin B6 for PMS.
Comment: A study of 630 women showed that
while 40 mg of Vitamin B6 produced no significant benefit, 100 mg to 150 mg
reduced PMS symptoms in about 66% of the women, while 160 mg to 200 mg of
Vitamin B6 reduced PMS symptoms in about 79% of the women. There was a
dose-dependent benefit, with 200 mg producing an optimal benefit. All nutrients
exhibit dose-dependent effects. Vitamin B6 as 200 mg is also the No Observed
Adverse Effect Level for Vitamin B6, so it is safe, in general.
|
Vitamin B6 Dose |
Reduction |
|
40 mg |
None |
|
100 mg – 150 mg |
66 percent |
|
160 mg – 200 mg |
79 percent |
Schellenberg
R, et al. Treatment for the
premenstrual syndrome with agnus castus
fruit extract: prospective, randomised, placebo
controlled study. British Medical Journal 2001 Jan 20;322:134-137.
Comment: A
double-blind, placebo-controlled 3-month study of premenstrual symptoms in 170
women (average age 36) showed that 20 mg of Vitex
extract reduced PMS symptoms about 28% better than placebo. The women noted
significant reductions in irritability, mood disturbances, anger, headache, and
breast fullness compared to placebo.
Author: Michael
Mooney. mmooney@covad.net
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